MYO/CK-MB/TROP I Combo Rapid Test

Description

Product information

The MYO/CK-MB/TROP I Combo Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid immunoassay for the qualitative detection of human cardiac Myoglobin, CK-MB and Troponin I (c Tnl) in whole blood, serum o plasma and assists in the diagnosis of myocardial infarction (MI).

Advantages of MYO/CK-MB/TROP I

• Easy to perform
• No complex sample collection needed
• Accurate test result

General information

The Myoglobin/CK-MB/Troponin I Combo Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid immunoassay for the qualitative detection of human cardiac Myoglobin, CK-MB and Troponin I (c Tnl) in whole blood, serum o plasma and assists in the diagnosis of myocardial infarction (MI). Myoglobin (MYO), Creatinine Kinase MB (CK-MB) and cardiac Troponin I (cTnl) are proteins released into the bloodstream following heart damage.

Myoglobin is a hemoprotein normally present in heart muscle and skeletal muscle with a molecular weight of 17.8 kDa. Myoglobin (MYO), Creatinine Kinase MB (CK-MB) and cardiac Troponin I (cTnl) are proteins released into the bloodstream following heart damage. Myoglobin is a hemoprotein normally present in heart muscle and skeletal muscle with a molecular weight of 17.8 kDa. When muscle cells are damaged, myoglobin is rapidly released into the blood due to its relatively small size.

Myoglobin level increases measurably above the reference standard in the 2-4 hours following the heart attack, peaking after 9-12 hours and returning to the standard value in 24-36 hours.2,3 CK-MB is a enzyme also present in heart muscle, with a molecular weight of 87.0 kDa.4 Creatinine Kinase is a dimeric molecule formed by two subunits called “M” and “B” which combine to form three different isoenzymes: CK-MM , CK-BB and CK-MB. CK-MB is the creatinine kinase isoenzyme most involved in the metabolism of cardiac muscle tissues. The release of CK-MB into the blood following IM can be detected in the 3-8 hours following the onset of symptoms. It peaks in 9-30 hours and returns to standard levels in 40-72 hours. Cardiac Troponin I is a protein found in heart muscle with a molecular weight of 22.5 kDa7. Troponin I is part of a complex of three subunits that includes Troponin T and Troponin C. Together with tropomyosin, this structural complex forms the main component that regulates the activity of actomyosin Calcium-ATpase in striated skeletal muscle and cardiac.

Following heart damage, Troponin I is released into the blood in the 4-6 hours following the onset of pain. The Troponin I delivery system is similar to that of CK-MB, but while CK-MB levels return to normal after 72 hours, Troponin I remains elevated for 6-10 days, thus providing a wider detection window for heart damage. The Myoglobin/CK-MB/Troponin I Combo Rapid Test Cassette (Whole Blood/Serum/Plasma) is a simple test that uses a combination of antibody-coated particles and captures reagents to qualitatively detect Myoglobin, CK-MB and Troponin I (c Human cardiac Tnl) in whole blood, serum or plasma. The minimum detection level is 50 ng/mL for Myoglobin, 5 ng/mL for CK-MB and 0.5 ng/mL for Troponin I.