Midstream Saliva 6-S-MED

Product information

The Drug Rapid Test Midstream Saliva 6-S detects 6 substances with specific result for each substance analyzed. This test is a lateral flow chromatographic immunoassay for the qualitative detection of multiple drugs and drug metabolites in saliva. This Saliva drug test detects: AMP40, MET40, COC,30 MOP40, THC10, MDMA50.

Advantages of Saliva test

• Easy to collect use, user friendly test
• No large sample needed
• Short detection window, suitable for workflow, traffic control and rehabilitation centers for acute testing procedures
• Drug test procedure in one-step due to the midstream
• Saliva sample is not easy to manipulate

General information

The Drug Rapid Test Midstream Saliva for AMP, MET, COC, OPI, THC, MDMA is an immunoassay based on the principle of competitive binding. Drugs that may be present in the oral fluid specimen compete against their respective drug conjugate for binding sites on their specific antibody. During testing, a portion of the oral fluid specimen migrates upward by capillary action. A drug, if present in the oral fluid specimen below its cut-off concentration, will not saturate the binding sites of its specific antibody. The antibody will then react with the drug-protein conjugate and a visible colored line will show up in the test line region of the specific drug strip. The presence of drug above the cut-off concentration in the oral fluid specimen will saturate all the binding sites of the antibody. Therefore, the colored line will not form in the test line region. A drug-positive oral fluid specimen will not generate a colored line in the specific test line region of the strip because of drug competition, while a drug-negative oral fluid specimen will generate a line in the test line region because of the absence of drug competition.
To serve as a procedural control, a colored line will always appear at the control line region, indicating that proper volume of specimen has been added and membrane wicking has occurred.

A rapid test for the simultaneous, qualitative detection of multiple drugs and drug metabolites in human saliva. For healthcare professionals including professionals at point of care sites. Immunoassay for in vitro diagnostic use only.

Test procedure

1. Allow the test Midstream, specimen, and/or controls to reach room temperature (15- 30°C) prior to testing. Instruct the donor to not place anything in the mouth including food, drink, gum or tobacco products for at least 10 minutes prior to collection.
2. Bring the pouch to room temperature before opening it. Remove the test from the sealed pouch and use it within one hour.
3. Take off the Device cap and collect oral fluid specimen as follows. Important: Place the tongue against the upper and lower jaws and roots to enrich the oral fluid. Insert the sponge end into the mouth, actively swab around the gums on both sides of the mouth (10-15 times) to assist saturation. Put the absorbent wick under the tongue to collect oral fluid until the flow appear in the test windows (approximately 60 seconds) and then take out the device and start a timer. If no flow appeared repeat the procedure in steps above until the flow appear. If no flow appeared after triplicate of steps above, discard the device, review procedures with the donor and repeat the test using a new device.
4. Place the test device on a clean and level surface.
5. Read the test result at 3-10 minutes. If all lines are clearly visible at 3 minutes or sooner, then the test can be interpreted as negative and discarded. If any lines are not visible at 3 minutes, then the test should be re-read at 10 minutes.

Interpretation of the results

Negative result: Two colored lines appear. One colored line should be in the control region (C), and another apparent colored line adjacent should be in the test region (Drug/T). This negative result indicates that the drug concentration is below the detectable level.

*NOTE: The shade of color in the test line region (Drug/T) will vary, but it should be considered negative whenever there is even a faint line.

Positive result: One colored line appears in the control region (C). No line appears in the test region (Drug/T). This positive result indicates that the drug concentration is above the detectable level.

Invalid result: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test panel. If the problem persists, discontinue using the lot immediately and contact your supplier.